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Critical Appraisal: Appraising a Diagnostic Test: D-Dimer

Categories: CC21, Common Competences, Critical Appraisal, Learning Session


Description: Critical Appraisal: Appraising a Diagnostic Test: D-Dimer

Learning Objectives

By the end of this session you will be able to:

  • Define the terms pre-test and post-test probability
  • Define the terms sensitivity, specificity and positive and negative predictive values
  • Explain the biases that occur in diagnostic studies
  • Define internal and external validity

Module References

  • Wells PS, Anderson DR, Rodger M et al. Evaluation of d-dimer in the diagnosis of suspected deep-vein thrombosis. N Engl J Med 2003;349:1227-1235.
  • Greenhalgh T. How to read a paper: papers that report diagnostic or screening tests. BMJ 1997;315:540-543.

One Comment

  1. Reuben Cooper says:

    Useful consolidation of appeasing a diagnostic test with useful explanations of specificity, sensitivity, PPV, and NPV – thanks!

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