Investigations

Explore the reasons why the following investigations might be carried out.

ECG

To diagnose atrial fibrillation or other cardiac arrhythmias or an acute cardiac event, which may be a source of emboli.

Bloods

Blood tests for acute limb ischaemia

Investigation Reason for investigation
Full blood count To detect haematological disorders predisposing to thrombosis
U&E Patients are often dehydratedPotassium may be raised if muscle necrosis has occurred
Glucose To screen for diabetes
Creatinine kinase May be raised if muscle ischaemia has occurred
Clotting It is rare to detect clotting abnormalities but it is usual to check before prescribing heparin
Group and save Patient may undergo surgery

Blood gas

To look for acidosis secondary to ischaemia.

If the patient is acidotic the most important initial management is rehydration.

Imaging

The urgency of imaging depends on the presentation. Conventional imaging consists of a digital subtraction angiogram. This is an invasive procedure using intra-arterial contrast but has the potential for therapeutic intervention (thrombolysis, angioplasty).

MR angiography and CT angiography are less invasive and should provide the same anatomical information. Arterial duplex is non-invasive but is operator dependent and iliac and calf vessels can be difficult to image. The choice of imaging is likely to depend on the local resources available.

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