A: Adrenaline

Adrenaline is the key life-saving drug.

Alarmingly, in the largest UK case series of fatal anaphylaxis, one-third received no adrenaline, and of the two-thirds who did, only 14% were given adrenaline pre-arrest [3].

Not on your shift surely….?

0.5 mg IM is the dose for over 12 years old and hopefully the paramedics will have beaten you to it. In which case, repeat if indicated.

Consider IV titrated adrenaline if experienced: 0.5 ml (50mcg) increments of a 1 mg in 10 ml pre-filled syringe (1 in 10,000) is what the UK Resuscitation Council recommend for experienced practitioners.