Anaphylaxis

Signs and Symptoms of Anaphylaxis

Incidence of Anaphylaxis

Allergic Response

Common Causes of Anaphylaxis

Pathophysiology

Differential Diagnosis

Emergency Treatment

Emergency Treatment 2 – Adrenaline

Emergency Treatment 3 – Other

Further Treatment

Further Management

Mast Cell Tryptase

3 Topics

Anaphylaxis – Post Test

Anaphylaxis – Post Test

Anaphylaxis Anaphylaxis – Post Test

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Question 1 of 10

1. Question
Which of the following statements is true about anaphylaxis?
- It is a type I hypersensitivity reaction
- It is a type II hypersensitivity reaction
- It is a type III hypersensitivity reaction
- It is a type IV hypersensitivity reaction
- It is a type V hypersensitivity reaction
Correct

Incorrect
Question 2 of 10

2. Question
Adrenaline-resistant anaphylaxis is occasionally seen in patients. Which of the following statements are true about the optimal treatment of this?
- Glucagon can be useful in patients who are taking beta-blockers
- Glucagon is useful in patients with C1 esterase inhibitor deficiency
- Fresh frozen plasma is the best treatment for patients with C1 esterase inhibitor deficiency
- C1 esterase inhibitor concentrate is the best treatment for patients with C1 esterase inhibitor deficiency
- Glucagon is the first line treatment for anaphylaxis patients who are taking β-blockers
Correct

Incorrect
Question 3 of 10

3. Question
Mast cell tryptase is released during anaphylactic reactions and is a valuable diagnostic aid.
What is the optimal time to take blood for mast cell tryptase levels?
- Only at the time of presentation
- At outpatients only
- At the time of presentation, 1-2 hours afterwards and when the patient has recovered
- At the time of presentation, 6-8 hours afterwards and when the patient has recovered
- Just before discharge
Correct

Incorrect
Question 4 of 10

4. Question
Mast cell tryptase is released during anaphylactic reactions and is a valuable diagnostic aid.
What is the optimal time to take a blood sample of mast cell tryptase to confirm the diagnosis of anaphylaxis?
- Before any treatment has been given
- Within one hour of arrival at the emergency department
- At outpatient follow-up
- Just before the patient is discharged
- Never
Correct

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Question 5 of 10

5. Question
What would be the first step in a 16 year old having acute anaphylactic reaction on peanut ingestion?
- Remove the trigger
- Attempt to make the patient vomit
- Attempt intravenous access
- Administer intramuscular adrenaline
- Administer oral steroids and antihistamine
Correct

Incorrect
Question 6 of 10

6. Question
Which of the following treatments needs to be instigated immediately in an acute anaphylactic reaction in a 12 year old?
- 3 ml of 1 in 1,000 IM adrenaline
- 0.3 ml of 1 in 1,000 IM adrenaline
- 0.3 ml of 1 in 1,000 IV adrenaline
- 0.3 ml of 1 in 10,000 IM adrenaline
- 0.3 ml of 1 in 1,000 SC adrenaline
Correct

Incorrect
Question 7 of 10

7. Question
What is the absolute contraindication for the administration of adrenaline in anaphylaxis?
- Coronary artery disease
- Uncontrolled hypertension
- Serious ventricular arrhythmias
- Second stage of labor
- None of the above
Correct

Incorrect
Question 8 of 10

8. Question
Which of the following treatments are useful in patients with anaphylaxis due to c1 esterase inhibitor deficiency?
- Hydrocortisone
- Adrenaline
- Fresh Frozen Plasma
- Chlorpheramine
- C1 esterase inhibitor concentrate
Correct

Incorrect
Question 9 of 10

9. Question
Which one of the following drugs are helpful in patients with anaphylaxis who are also taking beta-blockers and do not respond to adrenaline?
- Dobtamine
- Isoprenaline
- Glucagon
- Metoprolol
- Insulin
Correct

Incorrect
Question 10 of 10

10. Question
Which of the following statements about adrenaline preparations are true?
- 10 ml of 1 in 10,000 contains 1mg of adrenaline
- 10 ml of 1 in 1,000 contains 1 mg of adrenaline
- 0.5 ml of 1 in 10,000 contains 0.5 mg of adrenaline
- 0.5 ml of 1 in 1,000 contains 0.5 mg of adrenaline
Correct

Incorrect

9 Comments

Collapse Comments

Mr Christopher Busuttil October 30, 2023 at 10:12 pm

Useful revision, confirming my knowledge is consistent with current best practice. Interesting use of glucagon in b-blocker patients

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Dr Atif Munir December 3, 2023 at 10:31 pm

Learning Anaphylaxis in detail

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Hwei Choo December 6, 2023 at 4:14 pm

Thank you as revision

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Dr Abdul Majeed Mushtaq Shakir February 19, 2024 at 9:22 pm

Very useful revision

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Sunday Ekaidem February 28, 2024 at 10:45 am

Great session

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Dr Lucky Osakue Idemudia May 7, 2024 at 1:13 pm

great session

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Dr Hafiza Amber Noreen Fatima May 27, 2024 at 3:59 pm

Great session

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Tracy Tanner July 17, 2024 at 10:45 am

Fab session

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Dr Francis Oluwaseyi Awoyemi September 26, 2024 at 9:33 pm

great

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