Acceleration-deceleration forces acting directly on the mediastinum may cause cardiac contusion [6].
Air embolism can affect the coronary arteries and result in myocardial ischaemia and infarction [1,6,14].
Animal studies have demonstrated that a vagally-mediated response to thoracic blast injury results in a prolonged period of bradycardia with hypotension in the presence of normal systemic vascular resistance, which may explain why some patients with significant blast injury may be hypotensive without evidence of haemorrhage [6,12].