Causes

The following are causes of hypocalcaemia:

Low PTH
  • Hypoparathyroidism
  • Hypomagnesaemia
  • Hungry bone syndrome
High PTH
  • Vitamin D Deficiency: Dietary malabsorption or lack UVL
  • Renal failure: 1,25 OH D3 synthesis impaired renal osteodystrophy; retention PO42-
Other
  • Anticonvulsants
  • Massive transfusion
  • Acute rhabdomyolysis
  • Acute pancreatitis
  • Pseudohypoparathyroidism: End organ resistance to PTH
  • Pseudo-Pseudohypoparathyroidism: Phenotypic above but normal Ca2+ metabolism.
  • Osteomalacia
  • Rickets
  • Parathyroid removal
  • Di George syndrome
  • Malabsorption e.g. coeliac disease