Calcium Homeostasis: Vitamin D

The role of vitamin D is important in maintaining calcium homeostasis.

Skin

Ultraviolet (UV) light converts 7-dehydrocholesterol in the skin to cholecalciferol (vitamin D3) or pre-vitamin D is directly ingested.

Liver

Cholecalciferol is converted to 25-hydroxyvitamin D (calcidiol) in the liver.

Kidney

25-hydroxyvitamin D is converted to the active metabolite 1,25-dihydroxyvitamin D in the kidney.

PTH

Parathormone (PTH) stimulates resorption of Ca2+ and PO4.

 

Previous Topic
Back to Lesson
Next Topic