Clinical features also occur through two mechanisms:
- Both a low flow through a stenosed vessel and intimal damage can cause thrombus formation. This leads to embolic neurological sequelae
- The haematoma, with or without aneurysm formation, can cause symptoms from compression of adjacent structures
The development of a cervical artery dissection is usually associated with either trauma or connective tissue disease and most commonly occurs between 35-45 years of age.
The trauma involved can be trivial and there have been reports of cases following sneezing and yoga.
Risk factors include:
- Trauma
- Respiratory tract infection
- Fibromuscular dysplasia
- Cystic medial necrosis
- Marfan syndrome
- Ehlers-Danlos syndrome