Author: Susan Uí Bhroin / Editor: Sarah Edwards / Reviewer: Debkumar Chowdhury / Codes: PhC4, PhP2, PhP3, SLO3 / Published: 06/07/2021 / Reviewed: 28/04/2025
Just after midnight an ambulance arrives with a 26-year-old female patient. A takeaway owner had called the emergency services after she became unresponsive in his restaurant.
Her vitals are as follows:
• BP 90/40
• Heart rate 140
• Temperature 36.5C
• Respiratory Rate 22
• SpO2 85% on 100% O2 via non-rebreather mask
• GCS 10 (E4, V2, M4)
From the end of the bed you notice she is profoundly cyanosed despite receiving 100% O2.
Your FY2 successfully obtains an ABG and she reads the following results to you as you secure IV access:
• pH 7.28
• PO2 42kPa
• pCO2 3.5kPa
• HCO3 13
• Lactate 9.7
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Question 1 of 3
1. Question
What other result may be available on the blood gas that would aid your diagnosis?
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Question 2 of 3
2. Question
The methaemoglobin level on the ABG is 37%. You note that the patient’s SpO2 is still not coming above 85% despite the high pO2.
What is the physiological explanation for the cyanosis?
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Question 3 of 3
3. Question
You give the patient IV methylene blue to treat the methaemoglobinaemia and very quickly her vitals improve and she is more alert. She tells you that she bought a vial of “poppers” in a nightclub and drank it.
If methylene blue had been unsuccessful or unavailable, which of these treatments may also be beneficial?
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Module Content
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13 responses
Good recap of methaemoglobinemia treatment
Great case
Good refresher!
Nice Revision thanks.
good case
Good recap of Methemoglobinemia
Quick effective module. Thank you for the recap.
interesting case of poisoning
thanks
Very good case with good links for further reading around. Learning bite 1-2mg/kg over 5 min, if 20-30% MetHb. thank you.
Great Revision
Good bit of revision of a relatively rare presentation.
Very nice