Context

Almost a century ago French neurologists Guillain and Barré gave their name to Guillain-Barré Syndrome (GBS), after they described the cases of two soldiers who presented with acute paralysis and areflexia, and later recovered. GBS is an acute immune mediated polyneuropathy with several variant forms

The incidence of the disease is static at 1–2/100,000.

It is more common in men (1.5:1) and with advancing age.

In spite of advances in the understanding of the pathogenesis and treatment options, it remains a severe disease, which can be difficult to diagnose and treat.