Introduction

Patients with mild hypercalcaemia or with moderate hypercalcaemia who are asymptomatic should be monitored, have adequate fluid intake, and receive investigations and treatment for the underlying malignancy. Serial calcium measurement should be undertaken. Urgent treatment should be commenced patients with symptomatic moderate hypercalaemia or severe. [1]

Long term control of hypercalcaemia of hypercalcaemia of malignancy requires treatment of that underlying malignancy. [2] Until this can be achieved, primary treatment goals include:

1. General supportive measures
2. Correcting intravascular volume contraction
3. Enhancing renal excretion of calcium
4. Inhibiting accelerated bone resorption

Management of hypercalcaemia of malignancy may be complex, and it is recommended that clinicians consult local guidelines or the BMJ Best Practice algorithm. [2]