Author: Tay Xue Chao Brian Diaz / Editor: Thomas MacMahon / Reviewer: Faathima Musaamil / Codes: HC5, HP1, HP2, OncP1, SaP2, SLO1, SLO5 / Published: 16/01/2020 / Reviewed: 20/01/2025
A 3-year-old boy presents with a 3-day history of runny nose, cough, low grade fever, reduced oral intake and lethargy.
His mother is worried that he’s been getting frequent infections over the last few weeks. She’s noticed that he hasn’t been eating properly while he’s been off form and has lost some weight. He has had infrequent nose bleeds. She’s been to her GP, GP out of hours service and your ED with him on several occasions, and has been prescribed multiple courses of antibiotics with a trial of inhalers.
On examination, the patient appears pale and lethargic – certainly not his “usual happy self” according to mum. His airway is patent, but he does exhibit mild respiratory distress. On auscultation, you hear a mix of scattered crackles, wheeze, and transmitted upper airway sounds. His throat and ears are clear, and he has no rash or photophobia. You also notice some bruising around his arms and lower legs.
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Question 1 of 3
1. Question
Which of the following diagnoses do you need to consider? (Select all that apply)
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2. Question
What Emergency Department investigations will you order? (Select all that apply)
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3. Question
Full blood count shows Haemoglobin of 95 g/L and White Cell Count of 50 x10^9/L. You make a provisional diagnosis of ALL and admit him to paediatrics for further management.
The paediatric registrar notes the elevated K at 5.8 and considers tumour lysis syndrome as a possibility.
What laboratory findings may suggest tumour lysis syndrome? (Select all that apply)
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