No specific infection has been linked to Kawasaki disease, despite a variety of bacterial, fungal and viral pathogens having been investigated. There are a few soft signs that indicate an infectious aetiology is possible3,5.

  • Consistent peak in the number of cases reported in winter months, when childhood infections are at their most prevalent
  • Temporal clusters of epidemics reported in Japan, North America and other countries
  • Significant overlap of clinical features between Kawasaki disease and other infectious pathologies

There is no evidence that vaccine administration during childhood triggers Kawasaki disease7-10.

Learning Bite

28% of affected children will develop heart damage and 19% will have lasting coronary artery aneurysms.