Paediatric multisystem inflammatory syndrome temporally associated with Covid-19 (PIMS-TS) is often described as being similar to Kawasaki disease as both are systemic inflammatory conditions and both can present with prolonged fever and mucocutaneous signs. However Kawasaki disease is a distinct entity, particularly in relation to presentation, treatment and frequency of coronary artery complications.

Table 2. A comparison of Kawasaki disease and PIMS-TS

Kawasaki diseasePIMS-TS
Respiratory symptoms/coughRareCommon
GI DisturbanceUncommonCommon
Clotting abnormalitiesNot usually seenPE possible
Shock Heart failureNot usually seenPresent
Age<5Older children
Coronary aneurysmsCommonRare

Learning Bite

Kawasaki disease is a distinct entity from PIMS-TS.

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