Paediatric multisystem inflammatory syndrome temporally associated with Covid-19 (PIMS-TS) is often described as being similar to Kawasaki disease as both are systemic inflammatory conditions and both can present with prolonged fever and mucocutaneous signs. However Kawasaki disease is a distinct entity, particularly in relation to presentation, treatment and frequency of coronary artery complications.
Table 2. A comparison of Kawasaki disease and PIMS-TS
| Kawasaki disease | PIMS-TS | |
| Respiratory symptoms/cough | Rare | Common |
| GI Disturbance | Uncommon | Common |
| Clotting abnormalities | Not usually seen | PE possible |
| Shock Heart failure | Not usually seen | Present |
| Age | <5 | Older children |
| Coronary aneurysms | Common | Rare |
Learning Bite
Kawasaki disease is a distinct entity from PIMS-TS.