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Summarise the paper in 200 words. Discuss the study objective, design, population & setting, methods, results and conclusion.
What are the strengths of the study design?
What is the difference between a cohort study and a case control study?
What are validity and reliability?
What is internal and external validity?
What is a positive likelihood ratio? What is the positive likelihood ratio of a patient with a Canadian TIA score of ≥9? What about a score of ≥14?
What is a negative likelihood ratio? Calculate this for a Canadian TIA score of 3, 1, and -1.
What is figure 1 in the paper? What is the C-statistic? What is the AUC?
Review Figure 2 from the paper. What is the additive and absolute net reclassification index?
What are the limitations of the study?