MS is suspected when a young person presents several times with neurological symptoms that suggest different areas of pathology, often with resolution of prior symptoms.

Lower extremities are typically affected more than upper extremities.

Patients may describe sensations of:

  • Heaviness
  • Weakness
  • Stiffness

Physical examination will demonstrate:

  • Decreased strength
  • Increased tone
  • Babinski’s reflex (Image)
  • Impairment of:

    • Vibration sense
    • Proprioception
    • Pain detection
    • Temperature detection

Cerebral MS, though uncommon (affecting less than 5% of patients), can cause disabling loss of intellect and seizures.

The image displays Babinski’s reflex. Babinski negative is a normal reaction. A positive Babinski test is a common finding in patients with MS.