The emergency physician should be aware of the following issues:

  • The differential diagnosis of any patient presenting to the ED with respiratory failure of unknown cause should include neuromuscular respiratory failure
  • Complaints of shortness of breath or dysphagia, especially new onset, should be taken very seriously in MG patients
  • The clinical features of impending crisis can be subtle, especially in the MG patient with vague symptoms
  • The course of MG is difficult to predict
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