Gastro-oesophageal reflux: Basic science and pathophysiology

Vomiting and feeding difficulties account for up to 36% of neonates presenting to the ED¹
Visible regurgitation of feeds:^²
- Is a common physiological event (affects at least 40% of infants)
- Usually begins before 8 weeks of age
- May be frequent (5% have six or more episodes per day)
- Does not usually require investigation or treatment
- Is also known as gastro-oesophageal reflux (GOR)
Serious pathology is unlikely in well, hydrated infants without concerning features in the history or examination.³