Basic science and pathophysiology

  • A very common diagnosis that can also present with isolated regurgitation.
  • Typically an infant requires 150ml/kg/day to ensure adequate growth.
  • A fluid ounce is approximately 30ml.
  • This is more difficult to assess in breast-fed infants but may be apparent with a careful feeding history.
  • However, in both types of infant growth will be excessive.


  • If excessive feeding is suspected then this should be reduced to acceptable levels.
  • Parents should be advised to return if:
    • Persistently projectile, haematemesis or bilious vomiting
    • New concerns (marked distress, feeding difficulties or faltering growth)
    • Persistent, frequent regurgitation beyond the first year of life