Factors influencing tissue healing
Local Factors:
- Devitalized tissue
- Clot
- Foreign Bodies
- Infection
- Tissue hypoxia
- Acute Vascular damage or tight sutures
- Chronic
- Diabetic microvascular disease
- Atherosclerosis
- Venous Hypertension
Systemic factors:
- Nutritional deficiency Vitamin A, C, protein and zinc
- Drug treatment: glucocorticoids and cytotoxic drugs
- Diabetes
- Body irradiation
- Hypercatabolic states
- Neoplasia, Jaundice, Uremia, Burns