Author: Harry Spencer / Editor: Steve Corry-Bass / Codes: AP2, SeC3, SLO1, SLO2 / Published: 17/07/2025
A 38-year-old male presents with fever and a rash and concerns about what he believes are infected haemorrhoids. He has no past medical history.
The patient reports that over the last few weeks he has noticed haemorrhoids when wiping after defecation. They are not painful, he also reports feeling run down and feverish and is worried they may be infected. His GP prescribed a course of oral antibiotics but the patient stopped taking these after developing a rash. The patient has been taking fluoxetine for several years.
The patient is sexually active and has intercourse with male and female partners.
Observations:
- Heart Rate 68 beats per minute
- Blood Pressure 124/83 mmHg
- Respiratory Rate 16 breaths per minute
- Oxygen saturations on room air 98%
- Temperature 36.4°C
On examination:
The rash is prominent on the chest and is noted on the palms of hands and soles of feet. On PR examination there are several large flat warty-lesions surrounding the margin of the external anal sphincter with a moist surface and clear discharge. The lesions are prominent in the flexural folds.
You suspect Syphilis as a cause for the patients presentation.
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Question 1 of 3
1. Question
Given the presence of the following palmar rash and the likely diagnosis what is the name of the anal skin lesions that are commonly associated with this specific diagnosis?
Fig. 1 via CDC PHIL
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Question 2 of 3
2. Question
When screening the patient for other symptoms they deny any neurological, cardiac or ocular symptoms. What additional screening/examination should be performed or organised before discharging the patient?c
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Question 3 of 3
3. Question
The patient is referred to local sexual health screening services for further testing and it was decided to begin empirical treatment for potential neurosyphilis. They are then brought back to resus following a suspected allergic reaction. The patient was treated with antibiotics 30 minutes ago and quickly began to panic and fell to the floor. The patient began convulsing and an ambulance was called. On review in resus the patient is now calm and asymptomatic. They did not receive any benzodiazepines, the convulsive episode appears to have been self-limiting.
What was the likely cause of the patients symptoms?
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19 responses
Interesting case, many thanks!
good refresher
Excellent Case presentation.
Great Revision
interesting case
Good topic
Good review
Excellent case with good revision
Good module
Interesting & very timely case, thank you
nice learning
Very informative and nice case
Good
great
Interesting presentation.
excellent revision of forgotten subject
Good, thank you.
very interesting case
Very interesting case study.