Management and Pathophysiology

MVP is prolapse of a portion of the valve leaflets into the left atrium during systole associated with a small amount of regurgitation of blood. The condition is found in 2-5% of the population and occurs more commonly in women [10]. Most cases are idiopathic. It can be acquired secondary to IHD, rheumatic heart disease and hypertrophic cardiomyopathy.


One or both of the mitral valve leaflets show fibromyxomatous changes. At the end of diastole, the valve closes normally but as the pressure in the LV rises, the leaflet prolapses back into the LA. Strain on the papillary muscles can lead to mitral regurgitation.