Author: Catriona J Thompson / Editor: Yasmin Sultan / Reviewer: Ahmad Alabood / Codes: ELP3, SLO1, SLO4 / Published: 29/05/2023
A 72-year-old lady presents to a Minor Injuries Unit following head injury. On examination, evidence of suspected skull base fracture is found and she is, therefore, referred to the Emergency Department (ED) for radiological investigation.
On arrival at ED, she gives a history of having had a brief collapse leading to the head injury. The only feature of potential brain injury is vomiting, and there is blood evident in the right ear canal.
She appears slightly short of breath with saturations of 92% on low-flow oxygen. Systemically, she gives a history of dyspnoea on exertion for two weeks, and her accompanying friend has noticed a worsening cough over the preceding six weeks.
She has a background history of significant, but controlled Rheumatoid Arthritis for which she has been started on Methotrexate ten weeks previously.
Chest examination reveales bibasal fine, dry-sounding crackles, and some mild anterior pleuritic-type pain. Arterial blood gas shows hypoxia (PO2 <9 with FiO2 of around 24%). A CTPA is therefore performed to exclude pulmonary embolism, (see image shown). Subsequently she required invasive ventilation for hypoxia, and died ten days later.
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What is the most likely cause for the hypoxia and collapse?
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10 responses
An interesting case and a reminder to dig below the surface.
great
Not come across this, thanks
Have read about it but never come across a case, interesting.
I wasn’t aware of this causation
Indeed an interesting case….will be on my radar
An excellent reminder to think of recent changes and potential triggers
This is definitely a pit fall in those elderly falls. Always take a past medical history along with matching medication. This can definitely save a life or two. Thank you for the gentle reminder.
It’s always good to have a broad view and understand the etiology of the presenting symptoms.
Nice case