Author: Melanie Dyer / Editor: Steve Corry-Bass / Reviewer: Nikhil Tambe / Codes: CC11, CP1, CP2, CP4, GP1, ResP1, SLO1, SLO3 / Published: 07/10/2020 / Reviewed: 17/05/2025
A 57-year-old female presents with a history of being unable to exert herself when rushing for a bus with associated heavy central chest pain 5 days earlier. Over the subsequent days the chest pain persisted and she developed, exertional breathlessness, palpitations, epigastric pain radiating to her back and on the day of presentation to ED she had two syncopal episodes. She has a PMH of Hypertension and denies any recent illnesses.
On examination, she looks pale and unwell with a labile BP between 70-90 systolic; Her remaining observations were normal. She has a scattered wheeze bilaterally and guarding in the epigastrium and right upper quadrant with localised peritonism and Murphy’s sign is positive.

Initial Investigations:
ECG – ST elevation 1mm inferiorly and laterally
VBG: pH 7.289 [7.35-7.45], pCO2 6.14 [4.67-6.4], HCO3 19[19-28] lactate 5.7[0.5-1.6]
CXR – no consolidation.
Bloods:
High Sensitivity Troponin – 5 [0-3 negative; 4-120 moderate; >120 positive)
D dimer 21000 [0-500]
K+ 6.2 [3.5 -5.3]– Prescribed treatment for hyperkalaemia
A CTPA is requested based on raised D-dimer to rule out PE. CT abdomen ordered for a suspected abdominal visceral perforation or cholecystitis. CT Findings: 1. 2.5cm pericardial effusion 2. hepatic engorgement 3. Right heart strain 4. Right lung mass.
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Question 1 of 3
1. Question
What is the most likely cause of pericardial effusion in this patient?
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Question 2 of 3
2. Question
What are the ECG findings in Pericardial Effusion?
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3. Question
The following are the indications for pericardial drainage except:
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Module Content
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Syncope
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Breathlessness
Dyspnoea is an overall term used to describe an unpleasant awareness of increased respiratory effort and will be used synonymously with "breathlessness" in this session.
Pleural Effusion
This session looks at the assessment and management of the adult with a pleural effusion in the ED.
7 responses
Very interesting!
Very informative and interesting clinical case especially useful for the ECG findings
great read
Very good case
Nice One
interesting case
Interesting